Author

Marcel Wüthrich

University of Wisconsin–MadisonORCID 0000-0002-2781-7876Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 5 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Bruce S. KleiniD· 6 shared Cleison Ledesma TairaiD· 5 shared Lucas dos Santos DiasiD· 4 shared George R. ThompsoniD· 2 shared Sarah Lichtenberger· 2 shared Uju Joy OkaaiD· 2 shared Xin He· 2 shared Alexander J. WhiteheadiD· 1 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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6 shared papersImmunology

Bruce S. KleinORCID

Mutual co-authors in cluster

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6 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 16, 2026

An innate immune circuit involving the lectin pathway, complement and lung epithelial cells enforce barrier immunity to inhaled fungal disease

Darin L. Wiesner, Gaurav Bairwa, Desai Prashant…·Bruce S. Klein

DOI 10.64898/2026.06.15.732416

𝕏 PostBluesky

ImmunologymBioPeer-reviewedJun 11, 2026

Combination adjuvants drive long lived plastic Th17 cells that convert to multi-functional Th1 cells and protect mice against fungal infection

Marcel Wüthrich, Uju Joy Okaa, Cleison Ledesma Taira…·Bruce S. Klein

The paper shows that combination adjuvants drive Th17 cells that convert to multi-functional Th1 cells, enhancing antifungal immunity in mice.

2 citationstop 4%

mouseexperimental assay

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ImmunologybioRxivApr 23, 2026

Natural Killer Cell Granule Protein (NKG7) promotes the development of vaccine-induced anti-fungal Th1 cells

Marcel Wüthrich, Cleison Ledesma Taira, Lucas dos Santos Dias…·Bruce S. Klein

This study identifies NKG7 as a regulator that promotes anti-fungal Th1 cell development and converts Th17 cells into polyfunctional memory Th1 cells.

DOI 10.1371/journal.ppat.1014187

humanexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 20, 2026

Homotypic SLAMF1:SLAMF1 interactions between innate T cells and neutrophils activate fungal killing by neutrophils

Lindsay Suarez Lau, Sarah Lichtenberger, Cleison Ledesma Taira…·Marcel Wüthrich

This study identifies SLAMF1 as a key receptor mediating communication between innate T cells and neutrophils to enhance fungal killing.

DOI 10.64898/2026.02.19.706741

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 23, 2025

Endoglucanase-2 (Eng2), a conserved immunodominant antigen in dimorphic fungi that elicits immunity and resistance during infection

Uju Joy Okaa, Cleison Ledesma Taira, Lucas dos Santos Dias…·Bruce S. Klein

This study identifies Eng2 as a conserved antigen in dimorphic fungi that elicits protective immunity and memory T cell responses in mice and humans.

DOI 10.1101/2025.06.23.661097

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 4, 2025

Identification of a unique TUBB3+ cell population in the tuberculosis granuloma

Sarah Monard, Arnaud Métais, Maxime Pingret…·Olivier Neyrolles

The paper identifies a TUBB3+ cell population in TB granulomas across multiple species and patients, distinct from known cell types and present in other infections.

1 citation

mousenon-human primate

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