Bruce S. Klein

The paper shows that combination adjuvants drive Th17 cells that convert to multi-functional Th1 cells, enhancing antifungal immunity in mice.

This study identifies NKG7 as a regulator that promotes anti-fungal Th1 cell development and converts Th17 cells into polyfunctional memory Th1 cells.

This study identifies SLAMF1 as a key receptor mediating communication between innate T cells and neutrophils to enhance fungal killing.

This study uses single-cell RNA sequencing to analyze human airway epithelial cell responses to Aspergillus and Coccidioides, revealing distinct stress and cytokine pathways.

This study identifies Eng2 as a conserved antigen in dimorphic fungi that elicits protective immunity and memory T cell responses in mice and humans.

The paper identifies a TUBB3+ cell population in TB granulomas across multiple species and patients, distinct from known cell types and present in other infections.

This study identifies and characterizes airway Microfold (M) cells using single-cell transcriptomics, revealing their lineage, differentiation pathways, and functional role in antigen sampling via CR2-dependent endocytosis.