Author

Em SeGraves

University of California, San FranciscoORCID 0000-0002-2785-5610Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alma L. BurlingameiD· 1 shared Beiduo RaoiD· 1 shared Hiten D. MadhaniiD· 1 shared Irene BeuschiD· 1 shared Juan A. Osés-PrietoiD· 1 shared Michael K. StuderiD· 1 shared Stefanie JonasiD· 1 shared Susan LeiiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alma L. BurlingameORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintNov 13, 2022

Targeted high throughput mutagenesis of the human spliceosome reveals its in vivo operating principles

Irene Beusch, Beiduo Rao, Michael K. Studer…·Hiten D. Madhani

This study uses CRISPR-Cas9 base editing to target the human spliceosome and identifies functional sites and resistance substitutions, revealing SUGP1's role in spliceosome disassembly.

1 citation

humanCRISPR screen

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