Susan Lei

The paper describes a method to isolate and characterize lipoprotein classes in plasma, revealing unique lipidomic, proteomic, and small RNA signatures for each class.

The paper characterizes the phenotypic landscape of Cryptococcus neoformans by analyzing gene deletions and their fitness under various conditions, revealing novel biological insights.

The paper analyzes ATAC-seq data from iPSC-derived motor neurons of ALS patients and controls to identify disease-specific chromatin accessibility changes and their predictive power for disease progression.

This study uses CRISPR-Cas9 base editing to target the human spliceosome and identifies functional sites and resistance substitutions, revealing SUGP1's role in spliceosome disassembly.

The paper performs an integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients to identify dysregulated pathways and validate them in vivo and in postmortem data.