Author

Stefanie Jonas

ETH ZurichORCID 0000-0002-8751-6741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alma L. BurlingameiD· 1 shared Amena NabihiD· 1 shared Beiduo RaoiD· 1 shared Christian ArnoldiD· 1 shared David DomjaniD· 1 shared David GatfieldiD· 1 shared Em SeGravesiD· 1 shared Enes S. ArpaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMolecular Biology

Alma L. BurlingameORCID

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3 papers

Recent·Most cited

Molecular BiologyJournal of Molecular BiologyPeer-reviewedFeb 26, 2026

Active site assembly by SMG5 as a mechanism for SMG6 endonuclease licensing in nonsense-mediated mRNA decay

Enes S. Arpa, Michael John Taschner, Mara De Matos…·David Gatfield

The paper investigates how SMG5 licenses SMG6 endonuclease activity in NMD by forming a composite active site with SMG6 PIN domain.

5 citationstop 2%

humanprotein structure

Molecular BiologybioRxivPreprintJan 24, 2024

Mechanistic basis of gene-specific transcription regulation by the Integrator complex

Kevin Sabath, Amena Nabih, Christian Arnold…·Stefanie Jonas

This study identifies TF binding sites on the Integrator complex that mediate gene-specific transcription regulation and inducible transcriptional responses.

4 citations

Molecular BiologybioRxivPreprintNov 13, 2022

Targeted high throughput mutagenesis of the human spliceosome reveals its in vivo operating principles

Irene Beusch, Beiduo Rao, Michael K. Studer…·Hiten D. Madhani

This study uses CRISPR-Cas9 base editing to target the human spliceosome and identifies functional sites and resistance substitutions, revealing SUGP1's role in spliceosome disassembly.

1 citation

humanCRISPR screen