Author

Andrew L. Cooksy

San Diego State UniversityORCID 0000-0002-2794-4269Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrey A. BobkoviD· 1 shared Brittany M. ConleyiD· 1 shared Christal Dyane SohliD· 1 shared Diego Avellaneda Matteo· 1 shared Elene Albekioni· 1 shared Elizabeth A. KomivesiD· 1 shared Jamie M. SchifferiD· 1 shared Kaitlyn A. Sabo· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Andrey A. BobkovORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMay 6, 2024

Active site remodeling in IDH1 mutants drives distinct kinetic and potential resistance mechanisms

Matthew Mealka, Nicole A. Sierra, Diego Avellaneda Matteo…·Christal Dyane Sohl

This study compares the reaction mechanisms of two IDH1 mutants, finding that R132Q has optimized active site conformation for both conventional and neomorphic activity, potentially explaining resistance to inhibitors.

4 citations

humanprotein structure

𝕏 PostBluesky