Author

Brent Allen Hanks

Duke UniversityORCID 0000-0002-2803-3272Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Balamayooran TheivanthiraniD· 2 shared Michael P. PlebanekiD· 2 shared Y‐Van NguyeniD· 2 shared Georgia Marie BeasleyiD· 1 shared Kaylee A. VillarrealiD· 1 shared Mahere Rezazade Bazaz· 1 shared Michael AksuiD· 1 shared Michael S. SturdivantiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Balamayooran TheivanthiranORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tumor-derived Extracellular Vesicles Induce ER Stress to Drive Tolerogenic Dendritic Cell Development in the Tumor Microenvironment

X F Wang, Michael P. Plebanek, Y‐Van Nguyen, Mahere Rezazade Bazaz, Michael S. Sturdivant, Balamayooran Theivanthiran, Brent Allen Hanks

This paper shows tumor-derived extracellular vesicles induce ER stress in dendritic cells, promoting tolerogenic DCs that suppress antitumor immunity, and identifies PPAR-α inhibition as a potential therapeutic strategy.

bioRxiv · Feb 12, 2026 · PreprintImmunology

Gli2 Facilitates Tumor Immune Evasion and Immunotherapeutic Resistance by Coordinating Wnt Ligand and Prostaglandin Signaling

Nicholas C. DeVito, Y‐Van Nguyen, Michael Sturdivant, Michael P. Plebanek, Kaylee A. Villarreal, Nagendra Sastry Yarla, Vaibhav Jain, Michael Aksu, Georgia Marie Beasley, Balamayooran Theivanthiran, Brent Allen Hanks

This paper identifies Gli2 as a key driver of immune evasion and immunotherapy resistance in tumors through Wnt and prostaglandin signaling, offering a therapeutic target for combination immunotherapies.

Cancer Research · Feb 19, 2025Peer-reviewedCancer Biology