Author
Duke UniversityORCID 0000-0001-6387-9030Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Nicholas C. DeVito, Y‐Van Nguyen, Michael Sturdivant…·Brent Allen Hanks
This paper identifies Gli2 as a key driver of immune evasion and immunotherapy resistance in tumors through Wnt and prostaglandin signaling, offering a therapeutic target for combination immunotherapies.
Binita Chakraborty, Prabuddha Chakraborty, Michael C. Brown…·Donald Patrick McDonnell
This study shows that estrogens enhance tumor-associated macrophage efferocytosis, promoting immunosuppression, and demonstrates that targeting the E2/ER/CX3CR1 axis can reverse this effect and improve radiation therapy.
Wanying Miao, Vaibhav Jain, Madison Han…·Jennifer Y. Zhang
The paper shows that inhibiting UBE2N in Tregs enhances anti-tumor immunity without causing autoimmunity by converting Tregs into effector-like cells.