Author

Hyunjoo Jean Lee

Massachusetts Eye and Ear InfirmaryORCID 0000-0002-2814-6664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Benjamin R. ThomsoniD· 2 shared Haiyan GongiD· 2 shared Hoi‐Lam LiiD· 2 shared Constance E. RunyaniD· 1 shared Darryl R. OverbyiD· 1 shared Dilip K. DebiD· 1 shared Ester Reina‐TorresiD· 1 shared Evan Alexander ScottiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPhysiology

Benjamin R. ThomsonORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintSep 11, 2026

VEGFA-Positive Macrophages Regulate Aqueous Humor Outflow in Aged Mice and Humans

Naoki Kiyota, Yalu Zhou, Dilip K. Deb…·Susan E. Quaggin

This study identifies VEGFA-producing macrophages around Schlemm's canal as a compensatory mechanism maintaining aqueous humor outflow during aging and vascular stress, suggesting TIE2 activation as a therapeutic target.

DOI 10.64898/2026.08.20.746006

mousehuman

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PhysiologyJCI InsightPeer-reviewedMay 5, 2026

PROX1 loss in adult mouse Schlemm's canal causes permanent ocular hypertension

Sofia Lara Ochoa, Hoi‐Lam Li, Hyeohn Kim…·Benjamin R. Thomson

This study shows that loss of PROX1 in adult mouse Schlemm's canal leads to permanent ocular hypertension by converting the canal to a vein-like phenotype.

DOI 10.1172/jci.insight.203711

mouseexperimental assay

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