Dilip K. Deb

This study identifies VEGFA-producing macrophages around Schlemm's canal as a compensatory mechanism maintaining aqueous humor outflow during aging and vascular stress, suggesting TIE2 activation as a therapeutic target.

The paper identifies a PIEZO1-ANGPT2-ITGA9 signaling pathway in Schlemm's canal endothelium that regulates intraocular pressure and glaucoma.

This study creates a mouse model overexpressing VEGF-C in kidney progenitor cells, revealing increased lymphangiogenesis and a cystic kidney phenotype resembling human renal lymphangiectasia.