Hoi‐Lam Li

This study shows that endothelin-2 drives hypertension-related retinal dysfunction through neuroinflammation, independent of intraocular pressure, and identifies EDNRA as a therapeutic target.

This study identifies VEGFA-producing macrophages around Schlemm's canal as a compensatory mechanism maintaining aqueous humor outflow during aging and vascular stress, suggesting TIE2 activation as a therapeutic target.

This study shows that loss of PROX1 in adult mouse Schlemm's canal leads to permanent ocular hypertension by converting the canal to a vein-like phenotype.