Dimitrios Mougiakakos

The paper identifies an EBV-specific T cell program in MS patients that contributes to CNS autoimmunity through B cell and myeloid cell activation.

The paper uses proteomics to identify metabolic vulnerabilities in FLT3-ITD AML cells, showing lipid restriction restores midostaurin sensitivity.

This study shows glycolytic flux supports human Th1 cell identity and effector function through STAT1 O-glycosylation, with inhibition of glycolysis or O-glycosylation reducing IFN-gamma production.

The paper investigates how spatial separation of antigens affects cytotoxicity in CAR-TCR cells by analyzing clonotype dynamics and functional TCR contributions.

This study investigates how kinase inhibitors reshape the immunopeptidome in CML by altering HLA-I peptide presentation through three molecular mechanisms.

This study identifies CD36 as a metabolic checkpoint sustaining Th2 cell tissue residency in allergic asthma by regulating GATA3 and PPARγ expression and interactions with dendritic cells.

This study identifies xCT regulation pathways in colon cancer using patient-specific models and reveals potential therapeutic targets for chemotherapy resistance.

The paper identifies BCR::ABL1-independent survival mechanisms in CML using phosphoproteomics and computational analysis, highlighting FLT3 as a therapeutic target for TKI-resistant cases.