Author

Kevin T. Gobeske

Yale UniversityORCID 0000-0002-2850-9197Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Nenad ŠestaniD· 4 shared Shaojie MaiD· 4 shared Suel–Kee KimiD· 4 shared Akemi ShibataiD· 3 shared Alvaro DuqueiD· 3 shared Gabriel SantpereiD· 3 shared Mikihito ShibataiD· 3 shared Suvimal Kumar SindhuiD· 3 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Nenad ŠestanORCID

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4 papers

Recent·Most cited

Competing Programs Shape Cortical Sensorimotor-Association Axis Development

Jeremiah Tsyporin, Menglei Zhang, Cai Qi, Ashlea Segal, Xinyun Li, Hyo‐Jin Kim, Sang-Hun Choi, Ivan Pavlović, Sara Bandiera, Thomas S. Finn, Suel–Kee Kim, Akemi Shibata, Takumi Nakamura, Kohei Onishi, Ziqin Zhang, , Nenad Šestan

The paper presents the MIND model, showing that competing induction and exclusion programs shape the sensorimotor-to-association axis in the neocortex across species.

Nature · Jul 1, 2026Peer-reviewedNeuroscience

Human-specific features of the cerebellum and ZP2-regulated synapse development

Suel–Kee Kim, Adriana Cherskov, Aastha Sindhwani, Sang-Hun Choi, Hyojin Kim, Mingli Li, Menglei Zhang, Xoel Mato-Blanco, Yuting Liu, Nicola Micali, David Matthew Young, Mark Estación, Yueqi Zhang, Jose Manuel Ruiz-Jiménez, Anandita Nadkarni, , Nenad Šestan

The paper identifies human-specific transcriptomic and regulatory features in the cerebellum, including ZP2's role in synapse development and regulation.

Cell · Mar 1, 2026Peer-reviewedNeuroscience

Adaptive Evolution of Gene Regulatory Networks in Mammalian Neocortical Neurons

Zhuo Li, Navjot Kaur, Gabriel Santpere, Sydney Keaton Muchnik, Suvimal Kumar Sindhu, Cai Qi, Mikihito Shibata, Olivier Clément, Thomas Klarić, Xabier de Martin, Victor A Luria, Hyesun Cho, Mingfeng Li, Akemi Shibata, Andrew T.N. Tebbenkamp, , Nenad Šestan

The paper identifies mammalian-specific gene regulatory elements and their role in neocortical neuron subtype diversity and connectivity, linking them to neurodevelopmental disorders.

bioRxiv · May 20, 2025 · PreprintNeuroscience

Molecular programs of regional specification and neural stem cell fate progression in developing macaque telencephalon

Nicola Micali, Shaojie Ma, Mingfeng Li, Suel–Kee Kim, Xoel Mato-Blanco, Suvimal Kumar Sindhu, Jon I. Arellano, Tianliuyun Gao, Mikihito Shibata, Kevin T. Gobeske, Alvaro Duque, Gabriel Santpere, Nenad Šestan, PASKO T. RAKIC

The paper uses single-cell transcriptomics to identify molecular programs in developing macaque telencephalon, revealing primate-specific signaling and gene roles in regional specification and neural stem cell fate.

Science · Oct 12, 2023Peer-reviewedNeuroscience