Author
Yale UniversityORCID 0000-0002-6963-0508Unclaimed ORCID profile · follow to get notified of new preprints
11 papers
Recent·Most cited
Jon I. Arellano, PASKO T. RAKIC
The paper updates a model of connectivity from the entorhinal cortex to the dentate gyrus, revealing higher divergence and synaptic complexity than previously described.
Hippocampus · Aug 2, 2026Peer-reviewedNeuroscience
Joshua J. Breunig, Juan I. Arellano, G Kim, K Anighoro, C. Danielle Antonuk, Rachelle Levy, Aslam Abbasi Akhtar, J Molina, Masato Torii, K Hashimoto-Torii, Sofia Fertuzinhos, Martin H. Dominguez, L Grigereit, Moise Danielpour, PASKO T. RAKIC
This study shows that dynamin 2 is essential for neural stem cell maintenance through its role in endocytosis, which differentially regulates Notch ligand and receptor activity.
bioRxiv · Jun 12, 2026 · PreprintDevelopmental Biology
Shreyash Sonthalia, Brian R. Herb, Ricky S. Adkins, Joshua Orvis, Jinrui Liu, Xiangyu Liao, Qingjie Yu, Xoel Mato-Blanco, Alex M. Casella, Genevieve Stein-O’Brien, Brian Caffo, Ronna P. Hertzano, Anup Mahurkar, Jin-Chong Xu, Jesse A Gillis, , Carlo Colantuoni
The paper compiles a large transcriptomic dataset of neocortical development and uses joint matrix decomposition to identify conserved transcriptome dynamics across mammals and developmental stages.
Nature Neuroscience · Mar 25, 2026Peer-reviewedNeuroscience
Suel–Kee Kim, Adriana Cherskov, Aastha Sindhwani, Sang-Hun Choi, Hyojin Kim, Mingli Li, Menglei Zhang, Xoel Mato-Blanco, Yuting Liu, Nicola Micali, David Matthew Young, Mark Estación, Yueqi Zhang, Jose Manuel Ruiz-Jiménez, Anandita Nadkarni, , Nenad Šestan
The paper identifies human-specific transcriptomic and regulatory features in the cerebellum, including ZP2's role in synapse development and regulation.
Cell · Mar 1, 2026Peer-reviewedNeuroscience
Jon I. Arellano, PASKO T. RAKIC
The paper updates neuronal counts in the rat hippocampal formation by aggregating data from 89 studies, revealing significant differences from traditional estimates.
Hippocampus · Jan 1, 2026Peer-reviewedNeuroscience
Xoel Mato-Blanco, Suel–Kee Kim, Alexandre Jourdon, Shaojie Ma, Sang-Hun Choi, Alice Maria Giani, Miguel I. Paredes, Andrew T.N. Tebbenkamp, Fuchen Liu, Alvaro Duque, Flora Maria Vaccarino, Nenad Šestan, Carlo Colantuoni, PASKO T. RAKIC, Gabriel Santpere, Nicola Micali
The temporal analysis of gene regulatory networks in human neural stem cells reveals multiple early critical phases associated with cortical disorders and neuropsychiatric traits.
Nature Communications · Jul 9, 2025Peer-reviewedNeuroscience
Jon I. Arellano, PASKO T. RAKIC
This paper quantitatively models the decline of adult neurogenesis in rodents across age, showing a significant reduction in new neurons' proportion in the hippocampus.
Frontiers in Neuroscience · Jun 3, 2024Peer-reviewedNeuroscience
Nicola Micali, Shaojie Ma, Mingfeng Li, Suel–Kee Kim, Xoel Mato-Blanco, Suvimal Kumar Sindhu, Jon I. Arellano, Tianliuyun Gao, Mikihito Shibata, Kevin T. Gobeske, Alvaro Duque, Gabriel Santpere, Nenad Šestan, PASKO T. RAKIC
The paper uses single-cell transcriptomics to identify molecular programs in developing macaque telencephalon, revealing primate-specific signaling and gene roles in regional specification and neural stem cell fate.
Science · Oct 12, 2023Peer-reviewedNeuroscience
Hong Li, Alvaro Duque, PASKO T. RAKIC
This study investigates the origin and development of the claustrum in rhesus macaques, identifying its independent formation and molecular characteristics.
Proceedings of the National Academy of Sciences · Jul 5, 2023Peer-reviewedNeuroscience
Nicola Micali, Suel–Kee Kim, Marcelo Diaz-Bustamante, Genevieve Stein-O’Brien, Seungmae Seo, Joo Heon Shin, Brian G. Rash, Shaojie Ma, Yanhong Wang, Nicolas A. Olivares, Jon I. Arellano, Kristen R. Maynard, Elana Judith Fertig, Alan J. Cross, Roland W. Bürli, , Ronald D.G. McKay
The paper models the progression of human neural stem cells in vitro, showing they transition through organizer states before committing to cortical excitatory or inhibitory neuronal fates.
Cell Reports · May 1, 2020Peer-reviewedNeuroscience
Daniel Franjic, Jinmyung Choi, Mario Škarica, Chuan Xu, Qian Li, Shaojie Ma, Andrew T.N. Tebbenkamp, Gabriel Santpere, Jon I. Arellano, Ivan Gudelj, Lucija Rapan, André M. M. Sousa, PASKO T. RAKIC, Nenad Šestan
The paper identifies molecular diversity in adult hippocampal and entorhinal cells, revealing cell-type-specific properties related to Alzheimer's disease vulnerability.
bioRxiv · Dec 31, 2019 · PreprintNeuroscience