Mingfeng Li

The paper identifies mammalian-specific gene regulatory elements and their role in neocortical neuron subtype diversity and connectivity, linking them to neurodevelopmental disorders.

The paper uses single-cell transcriptomics to identify molecular programs in developing macaque telencephalon, revealing primate-specific signaling and gene roles in regional specification and neural stem cell fate.

This study shows that VEGF-C overexpression enhances brain fluid drainage, provides neuroprotection, and improves stroke outcomes in mice.

The paper identifies primate-specific astrocyte responses to stroke, showing NogoA limits macrophage infiltration and suggests therapeutic targeting.

AC-PCA reduces dimensionality and adjusts for confounding variation in biological datasets, recovering anatomical structure and shared variation across species.