Molecular BiologyThe EMBO JournalPeer-reviewed
Bacterial ubiquitin ligase engineered for small molecule and protein target identification
James S. Ye, Abir Majumdar, Brenden C. Park…·Vincent S. Tagliabracci
This paper introduces SidBait, a modular proximity ligation approach to identify small molecule and protein targets, validated with known interactions and applied to discover new targets like CaMKII and CapZ.