Author

Abir Majumdar

Howard Hughes Medical InstituteORCID 0000-0002-3516-5855Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Adam OsinskiiD· 2 shared Joseph M. ReadyiD· 2 shared Kelly A. ServageiD· 2 shared Krzysztof PawłowskiiD· 2 shared Vincent S. TagliabracciiD· 2 shared Brenden C. Park· 1 shared Bruce A. PosneriD· 1 shared Diana R. TomchickiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Adam OsinskiORCID

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2 papers

Recent·Most cited

Bacterial ubiquitin ligase engineered for small molecule and protein target identification

James S. Ye, Abir Majumdar, Brenden C. Park, Miles H. Black, Ting‐Sung Hsieh, Adam Osinski, Kelly A. Servage, Kartik Kulkarni, Jacinth Naidoo, Neal M. Alto, Margaret M. Stratton, Dominique Alfandari, Joseph M. Ready, Krzysztof Pawłowski, Diana R. Tomchick, Vincent S. Tagliabracci

This paper introduces SidBait, a modular proximity ligation approach to identify small molecule and protein targets, validated with known interactions and applied to discover new targets like CaMKII and CapZ.

The EMBO Journal · Jan 3, 2026Peer-reviewedMolecular Biology

Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine

Genaro Hernandez, Adam Osinski, Abir Majumdar, Jennifer L. Eitson, Monika I. Antczak, Krzysztof Pawłowski, Hanspeter Niederstrasser, Kelly A. Servage, Bruce A. Posner, John W. Schoggins, Joseph M. Ready, Vincent S. Tagliabracci

The paper identifies NCI-2, a covalent inhibitor of the SARS-CoV-2 NiRAN domain, and presents a structural blueprint for drug design.

Journal of Biological Chemistry · Mar 4, 2025Peer-reviewedBiochemistry