This study uses cryo-ET to analyze the ultrastructure of silkworm, spider, and artificial silk, revealing differences in their fundamental structural units and hierarchical organization.

bioRxiv · Mar 12, 2025 · PreprintBiophysics

Multi-trait genome-wide association study in 34,394 Chinese women reveals the genetic architecture of plasma metabolites during pregnancy

SiYang Maggie Liu, Jilong Yao, Liang Lin, Xianmei Lan, Linlin Wu, Xuelian He, Nannan Kong, Yan Li, Yuqing Deng, Jiansheng Xie, Huanhuan Zhu, Xiaoxia Wu, Zilong Li, Likuan Xiong, Yuan Wang, , Siqi Liu

This study identifies 30 novel metabolite-gene associations in 34,394 Chinese pregnant women and finds pleiotropy and causal relationships between metabolites and diseases.

Cell Genomics · Oct 1, 2024Peer-reviewedGenetic & Genomic Medicine

Rapid, sensitive, full genome sequencing of Severe Acute Respiratory Syndrome Virus Coronavirus 2 (SARS-CoV-2)

Clinton R. Paden, Ying Tao, Krista J. Queen, Jing Zhang, Yan Li, Anna Uehara, Suxiang Tong

The paper describes validated protocols for rapid, sensitive full-genome sequencing of SARS-CoV-2 using multiplex RT-PCR with MinION/MiSeq or singleplex nested RT-PCR with Sanger sequencing.

Emerging infectious diseases · Jul 1, 2020Peer-reviewedGenomics