Junaid M. Afzal

This study shows cyclic hypoxia promotes breast cancer growth through WNT5A-ROR1 signaling between stromal and tumor cells in a co-culture model.

The paper identifies genes associated with stromal resistance to placental and cancer invasion by comparing species and analyzing fibroblast responses.

The paper shows oscillatory hypoxia induces a unique gene expression signature in breast cancer linked to poor survival.

This study shows that stable and oscillatory hypoxia differentially regulate the invasiveness of breast cancer-associated fibroblasts through distinct molecular and mechanical mechanisms.