Kshitiz Gupta

This study shows cyclic hypoxia promotes breast cancer growth through WNT5A-ROR1 signaling between stromal and tumor cells in a co-culture model.

The paper identifies genes associated with stromal resistance to placental and cancer invasion by comparing species and analyzing fibroblast responses.

The paper models and experimentally validates how HIF-1 dynamics in cycling hypoxia lead to specific gene expression patterns linked to cancer progression.

The paper shows oscillatory hypoxia induces a unique gene expression signature in breast cancer linked to poor survival.

This study shows that stable and oscillatory hypoxia differentially regulate the invasiveness of breast cancer-associated fibroblasts through distinct molecular and mechanical mechanisms.

The paper introduces a method combining lightsheet microscopy with optical visco-elastography to analyze single-cell mechanics and fluorescence in 3D live tissues, revealing new insights into cellular interactions.

This study investigates how rhPRG4 affects TNFα-induced inflammation in corneal epithelial cells, finding it reduces NFκB activity and FAT10 expression.