Cyclic Hypoxia drives Wnt5a-ROR1 stroma-tumor crosstalk promoting breast cancer growth
Yamin Liu, Shaofei Liu, Sarthak Sahoo, Xirui Wang, Wenqiang Du, David D. Ellison, Junaid M. Afzal, Yasir Suhail, Mohit Kumar Jolly, Kshitiz Gupta
This study shows cyclic hypoxia promotes breast cancer growth through WNT5A-ROR1 signaling between stromal and tumor cells in a co-culture model.
bioRxiv · Oct 13, 2026 · PreprintCancer Biology