Author

Dmitri K. Klimov

George Mason UniversityORCID 0000-0002-2893-867XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Bryan M. Delfing· 2 shared Christopher LockhartiD· 2 shared Han YangiD· 2 shared Mohsin Saleet JafriiD· 2 shared Sameer Tiwari· 2 shared Yuntao WuiD· 2 shared Abdul A. WaheediD· 1 shared Amrita Haikerwal· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Bryan M. Delfing

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2 papers

Recent·Most cited

The decameric repeat (DR) of PSGL-1 functions as a basic antiviral unit in restricting HIV-1 infectivity

Han Yang, Leanna Sealey, Yajing Fu, Bryan M. Delfing, Christopher Lockhart, Linda D. Chilin, Sameer Tiwari, Mohsin Saleet Jafri, Dmitri K. Klimov, Yuntao Wu

This study identifies the decameric repeat (DR) of PSGL-1 as an essential antiviral unit that restricts HIV-1 infectivity by hindering virion attachment to target cells.

bioRxiv · May 14, 2025 · PreprintImmunology

PSGL-1 excludes HIV Env from virion surface through spatial hindrance involving structural folding of the decameric repeats (DR)

Sameer Tiwari, Bryan M. Delfing, Han Yang, Christopher Lockhart, Amrita Haikerwal, Abdul A. Waheed, Eric O. Freed, Mohsin Saleet Jafri, Dmitri K. Klimov, Yuntao Wu

This study identifies PSGL-1's decameric repeats as critical for excluding HIV Env from virions through structural folding that spatially hinders Env incorporation.

bioRxiv · Dec 28, 2024 · PreprintMicrobiology