Author

Linda D. Chilin

George Mason UniversityORCID 0000-0002-1382-1874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Yuntao WuiD· 2 shared Bryan M. Delfing· 1 shared Christopher LockhartiD· 1 shared Dmitri K. KlimoviD· 1 shared Farhang AlemiD· 1 shared Han YangiD· 1 shared Laia Gharavi-naeini· 1 shared Leanna SealeyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Yuntao WuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

HSV-1 infection induces brain cofilin hyperphosphorylation in the 5xFAD Alzheimer's Disease mouse model

Laia Gharavi-naeini, Zhenfeng Shu, Farhang Alem, Shu Feng, Linda D. Chilin, Pinghui Feng, Yuntao Wu

This study shows HSV-1 infection increases cofilin phosphorylation in 5xFAD mice, linking viral infection to AD pathology through actin cytoskeleton disruption.

bioRxiv · Aug 10, 2025 · PreprintMicrobiology

The decameric repeat (DR) of PSGL-1 functions as a basic antiviral unit in restricting HIV-1 infectivity

Han Yang, Leanna Sealey, Yajing Fu, Bryan M. Delfing, Christopher Lockhart, Linda D. Chilin, Sameer Tiwari, Mohsin Saleet Jafri, Dmitri K. Klimov, Yuntao Wu

This study identifies the decameric repeat (DR) of PSGL-1 as an essential antiviral unit that restricts HIV-1 infectivity by hindering virion attachment to target cells.

bioRxiv · May 14, 2025 · PreprintImmunology