Molecular BiologyCell ReportsPeer-reviewed
Structural differences between pri-miRNA paralogs promotes alternative Drosha cleavage and expands target repertoires
Xavier Bofill‐De Ros, Wojciech K. Kasprzak, Yuba R. Bhandari…·Shuo Gu
The paper shows that structural differences in pri-miRNA paralogs lead to alternative Drosha cleavage, generating miRNAs with expanded target repertoires and distinct roles in tumor progression.
63 citations