Author

Marie‐Louise T. Monaghan

University of Colorado AnschutzORCID 0000-0002-2907-3903Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Katharina HoppiD· 2 shared Berenice Y. GitomeriD· 1 shared Dustin T. Nguyen· 1 shared Emily K. KleczkoiD· 1 shared Eric T. ClambeyiD· 1 shared Jost KlawitteriD· 1 shared Katherine I. Swenson-FieldsiD· 1 shared Michael Peter VitekiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPharmacology & Toxicology

Katharina HoppORCID

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2 papers

Recent·Most cited

Anti-Polyamine Therapy Restrains Kidney Cyst Growth in an Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease

Katharina Hopp, Marie‐Louise T. Monaghan, Sizhao Lu, Timothy A. Fields, Michael Peter Vitek, Katherine I. Swenson-Fields

This study tests DFMO, an FDA-approved drug, in a mouse model of ADPKD and finds it reduces kidney cyst growth and improves kidney health.

bioRxiv · Jun 5, 2026 · PreprintPharmacology & Toxicology

The Tryptophan Metabolizing Enzyme Indoleamine 2,3-Dioxygenase 1 Regulates Polycystic Kidney Disease Progression

Dustin T. Nguyen, Emily K. Kleczko, Nidhi Dwivedi, Marie‐Louise T. Monaghan, Berenice Y. Gitomer, Michel B. Chonchol, Eric T. Clambey, Raphael A. Nemenoff, Jost Klawitter, Katharina Hopp

This study shows that IDO1 inhibition reduces ADPKD severity by altering the cystic immune microenvironment.

JCI Insight · Nov 24, 2022Peer-reviewedMolecular Biology