Author

Eric T. Clambey

University of Colorado AnschutzORCID 0000-0002-7972-9544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Gabrielle VrageliD· 2 shared Linda Faye van DykiD· 2 shared Rachael E. KosteleckyiD· 2 shared Andrew E. GoodspeediD· 1 shared Berenice Y. GitomeriD· 1 shared Christoph WeigeliD· 1 shared Darby G. OldenburgiD· 1 shared Derek W. AbbottiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Gabrielle VragelORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HIGH DOSE GAMMAHERPESVIRUS INFECTION IN MACROPHAGES RESULTS IN INFLAMMATORY MULTIMODAL CELL DEATH

Gabrielle Vragel, Gracyn Nelson-Reid, Rachael E. Kostelecky, Elizabeth Spear, Moses Lee, Derek W. Abbott, Linda Faye van Dyk, Eric T. Clambey

This study shows high-dose MHV68 infection of macrophages causes inflammatory cell death independent of lytic replication, involving autophagy and pyroptosis.

bioRxiv · Sep 19, 2026 · PreprintMicrobiology

Cytokine signaling regulates multiple stages of gammaherpesvirus infection in myeloid cells

Rachael E. Kostelecky, Gabrielle Vragel, Pedro Gámez, Eva Margarita Medina, Darby G. Oldenburg, Andrew E. Goodspeed, Christoph Weigel, Robert A. Baiocchi, Eric T. Clambey, Linda Faye van Dyk

This study shows that IFNγ and IL-4 regulate lytic infection in myeloid cells via JAK/STAT signaling, with IFNγ restricting lytic replication through multiple mechanisms.

bioRxiv · Sep 8, 2026 · PreprintImmunology

The Tryptophan Metabolizing Enzyme Indoleamine 2,3-Dioxygenase 1 Regulates Polycystic Kidney Disease Progression

Dustin T. Nguyen, Emily K. Kleczko, Nidhi Dwivedi, Marie‐Louise T. Monaghan, Berenice Y. Gitomer, Michel B. Chonchol, Eric T. Clambey, Raphael A. Nemenoff, Jost Klawitter, Katharina Hopp

This study shows that IDO1 inhibition reduces ADPKD severity by altering the cystic immune microenvironment.

JCI Insight · Nov 24, 2022Peer-reviewedMolecular Biology