Veronika Sander

The paper describes a scalable method to generate cystic ureteric bud organoids from PKD2-deficient hPSCs for ADPKD drug discovery, identifying a nutrient conjugate that reduces cyst formation.

The paper shows that partial repair after urinary obstruction reversal causes permanent structural and functional defects in the renal papilla in mice.

This study uses human kidney organoids to model acute kidney injury induced by cisplatin, finding that repeated low-dose treatment reduces toxicity while maintaining AKI responses.

This paper introduces a simple, inexpensive method to generate kidney organoids from human pluripotent stem cells, showing they develop tubular structures by day 8 and resemble fetal kidney structures by day 14.