Author

Joelle El Hokayem

Massachusetts General HospitalORCID 0000-0002-2919-692XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alessandro SammarcoiD· 1 shared Baolong SuiD· 1 shared Çağrı ÇakiciiD· 1 shared Christian E. BadriD· 1 shared Giorgia GuerraiD· 1 shared Hayk MnatsakanyaniD· 1 shared Katharina M. EymeiD· 1 shared Kelly T. KennewickiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alessandro SammarcoORCID

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1 paper

Recent·Most cited

Targeting SCD triggers lipotoxicity of cancer cells and enhances anti-tumor immunity in breast cancer brain metastasis mouse models

Alessandro Sammarco, Giorgia Guerra, Katharina M. Eyme, Kelly T. Kennewick, Qiao Yu, Joelle El Hokayem, Kevin J. Williams, Baolong Su, Çağrı Çakici, Hayk Mnatsakanyan, Valentina Zappulli, Steven J. Bensinger, Christian E. Badr

This study shows that inhibiting SCD in breast cancer brain metastases induces lipotoxicity and enhances anti-tumor immunity, improving survival in mouse models.

Communications Biology · Apr 4, 2025Peer-reviewedCancer Biology