The obesity associated BDNF intron-3 cis-regulatory element, BE5.1, modulates the effects of early-life stress on weight gain, anxiety and gene expression in a sex dependent manner.
Andrew R. McEwan, Joseph Morgan, Greg Hutchings…·Alasdair MacKenzie
The paper investigates how the BDNF intron-3 cis-regulatory element BE5.1 influences the effects of early-life stress on weight gain, anxiety, and gene expression, showing sex-dependent differences.