Author

Eleanor J. Tuck

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

David G. FrickeriD· 3 shared Noboru H. KomiyamaiD· 3 shared Seth G. N. GrantiD· 3 shared Douglas StrathdeeiD· 2 shared Karen E. Strathdee· 2 shared Kathryn A. Elsegood· 2 shared Louie N. van de LagemaatiD· 2 shared Mike D. R. Croning· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

David G. FrickerORCID

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4 papers

Recent·Most cited

A brain atlas of synapse protein lifetime across the mouse lifespan.

Edita Bulovaite, Zhen Qiu, Maximilian Kratschke, Adrianna Zgraj, David G. Fricker, Eleanor J. Tuck, Ragini Gokhale, Babis Koniaris, Shekib A. Jami, Paula Merino‐Serrais, Elodie Husi, Lorena Mendive‐Tapia, Marc Vendrell, Thomas J. O’Dell, Javier DeFelipe, , Seth G. N. Grant

The paper quantifies PSD95 protein lifetime in mouse synapses across lifespan and brain regions, revealing distinct patterns linked to development, behavior, and aging.

Neuron · Oct 5, 2022Peer-reviewedNeuroscience

Whole genome CRISPR screens identify a LRRK2-regulated pathway for extracellular tau uptake by human neurons

Lewis Evans, Alessio Strano, Eleanor J. Tuck, Ashley Campbell, James C. Smith, Christy Hung, Tiana S. Behr, Bernardino Francesco Ghetti, Benjamin Falcon, Emre Karakoç, Francesco Iorio, Alastair D. Reith, Andrew R. Bassett, Frederick J. Livesey

The paper identifies LRRK2-regulated pathways for extracellular tau uptake in human neurons using CRISPR screens, showing LRRK2's role in monomeric tau endocytosis.

bioRxiv · Aug 11, 2020 · PreprintNeuroscience

Synaptic combinatorial molecular mechanisms generate repertoires of innate and learned behavior

Noboru H. Komiyama, Louie N. van de Lagemaat, Lianne E. Stanford, Charles M. Pettit, Douglas Strathdee, Karen E. Strathdee, David G. Fricker, Eleanor J. Tuck, Kathryn A. Elsegood, Tomás J. Ryan, Jess Nithianantharajah, Nathan Skene, Mike D. R. Croning, Seth G. N. Grant

The paper identifies synaptic protein combinations that underlie diverse innate and learned behaviors in mice, showing their role in behavioral repertoire expansion and disease susceptibility.

bioRxiv · Dec 19, 2018 · PreprintNeuroscience

A combinatorial postsynaptic molecular mechanism converts patterns of nerve impulses into the behavioral repertoire

Maksym V. Kopanitsa, Louie N. van de Lagemaat, Nurudeen O. Afinowi, Douglas Strathdee, Karen E. Strathdee, David G. Fricker, Eleanor J. Tuck, Kathryn A. Elsegood, Mike D. R. Croning, Noboru H. Komiyama, Seth G. N. Grant

The paper identifies a combinatorial molecular mechanism in synapses that converts nerve impulse patterns into diverse behavioral responses across species and timescales.

bioRxiv · Dec 19, 2018 · PreprintNeuroscience