Author

Marlene Uglebjerg Fruergaard

Aarhus UniversityORCID 0000-0002-2963-992XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adriana KatziD· 1 shared Ana V. AlmeidaiD· 1 shared Birthe Brandt KragelundiD· 1 shared Emil E. TranchantiD· 1 shared Gregers Rom AnderseniD· 1 shared Heidi Gytz OleseniD· 1 shared Henrik PederseniD· 1 shared Ida B. Thøgersen· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Adriana KatzORCID

Author profile →

2 papers

Recent·Most cited

Active Conformations of Neuronal Na+,K+-ATPase isoforms and a Disease-Causing Mutant

Mads Eskesen Christensen, Michael Habeck, Adriana Katz, Marlene Uglebjerg Fruergaard, Yoav Peleg, Uri Pick, STEVEN J. D. KARLISH, Poul Nissen

The paper reports cryo-EM structures of Na+,K+-ATPase isoforms and a disease-causing mutant, revealing conformational states and functional properties related to Na+ transport and disease mechanisms.

Nature Communications · Jul 29, 2026Peer-reviewedBiochemistry

Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring

Trine Amalie Fogh Gadeberg, Martin Høgholm Jørgensen, Heidi Gytz Olesen, Josefine Lorentzen, Seandean L. Harwood, Ana V. Almeida, Marlene Uglebjerg Fruergaard, Rasmus K. Jensen, Philipp Kanis, Henrik Pedersen, Emil E. Tranchant, Steen Vang Petersen, Ida B. Thøgersen, Birthe Brandt Kragelund, Joseph Anthony Lyons, , Gregers Rom Andersen

This study uses cryo-EM to analyze the structural changes in C3 during hydrolysis, revealing a dynamic opening in the macroglobulin ring that allows domain translocation.

Nature Structural & Molecular Biology · Jan 23, 2025Peer-reviewedBiochemistry