Author
Aarhus UniversityORCID 0000-0003-0218-4862Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Amalie Benfeldt Purup, Pauline Funke, Cédric Montigny…·Guillaume Lenoir
The paper shows that the Drs2-Cdc50 flippase complex transports multiple anionic lipids, not just phosphatidylserine, and identifies the role of the water network in substrate recognition.
Trine Amalie Fogh Gadeberg, Martin Høgholm Jørgensen, Heidi Gytz Olesen…·Gregers Rom Andersen
This study uses cryo-EM to analyze the structural changes in C3 during hydrolysis, revealing a dynamic opening in the macroglobulin ring that allows domain translocation.
Stephanie Vrijsen, Rania Abou El Asrar, Marine Houdou…·Peter Vangheluwe
The paper functionally characterizes ATP13A2 variants linked to neurodegenerative disorders, finding that only the homozygous NCL variant causes complete loss-of-function, while others show subtle defects.
Milena Timcenko, Joseph Anthony Lyons, Dovile Januliene…·Poul Nissen
The paper determines the structures of the P4-ATPase Drs2p-Cdc50p using cryo-EM, revealing autoinhibition and PI4P-dependent activation mechanisms.