Vitali Sikirzhytski

The paper introduces SPaCe-MC, a statistical method to detect localized diffusion changes near stress granules, revealing consistent local constraints despite varied global cytoplasmic responses.

This paper optimizes genetically encoded nanoparticle expression to improve single-particle tracking of cytoplasmic diffusion in mammalian cells, showing increased diffusivity and better tracking quality.

This paper shows that 4-octyl-itaconate reduces HIV and cocaine-induced neurotoxicity and inflammation by modulating microglial activity and anti-inflammatory pathways.

This study identifies DDX3 inhibition as a potential therapy for HAND by blocking Tat and cocaine-induced microglial activation and neurotoxicity in rat and mouse models.