David‐Paul Minde

The paper identifies a hypervascular, BBB-compromised state in aging mice linked to cognitive decline and shows pharmacological stabilization improves vascular and cognitive outcomes.

LipiGo is a DNA-lipid nanoparticle hybrid that enables efficient delivery of functional mRNA to non-hepatic tissues, particularly the spleen, through passive redistribution and active targeting.

This study identifies Drosophila nAChR subunits interacting with insecticidal toxins using CRISPR/Cas9 and pull-down assays, providing insights for insecticide design.

The paper shows that intrinsically disordered regions (IDRs) are more accessible to in vivo biotinylation, linking predicted IDRs to biotinylation density across multiple proteomics studies.