Danial Asgari

Pleiotropy constrains the evolution of immune system plasticity while promoting domain modularity

The paper examines how pleiotropy affects evolutionary rates and plasticity in immune system genes across six Drosophila species, finding domain-specific evolution can reduce gene-level constraints.

How the Structure of Signaling Regulation Evolves: Insights from an Evolutionary Model

This paper develops an evolutionary model of immune signaling to show that downstream negative feedback loops evolve more robustly than upstream ones due to stronger selective pressures.

Resources modulate developmental shifts but not infection tolerance upon coinfection in an insect system

The paper investigates how dietary resources affect developmental shifts and infection tolerance in flour beetles coinfected with gregarine and bacterial parasites, finding that resources modulate developmental timing but not resistance to bacterial infection.

Induction and inhibition of Drosophila X chromosome gene expression are both impeded by the dosage compensation complex

The paper examines how DCC binding affects gene expression changes on the X chromosome in Drosophila under various treatments, finding that DCC-bound genes are less likely to be up- or down-regulated.