Author

Lindsey A. Kuchenbecker

Mayo ClinicORCID 0000-0002-2987-1040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aishe Kurti· 1 shared Akhilesh PandeyiD· 1 shared Axel D. MenesesiD· 1 shared Benjamin J. MaddeniD· 1 shared Bianca M. Opdenbosch· 1 shared Cassandra L. RosenbergiD· 1 shared Cheyenne D. HurstiD· 1 shared Chia‐Chen LiuiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Aishe Kurti

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Nomination of a novel plasma protein biomarker panel capable of classifying Alzheimer's disease dementia with high accuracy in an African American cohort

Lindsey A. Kuchenbecker, Kevin J. Thompson, Cheyenne D. Hurst, Bianca M. Opdenbosch, Michael G. Heckman, Joseph S. Reddy, Thuy Nguyen, Heidi L. Casellas, Katie D. Sotelo, Delila J. Reddy, John A. Lucas, Gregory Scott Day, Floyd B. Willis, Neill R. Graff‐Radford, Nilüfer Ertekin‐Taner, , Minerva M. Carrasquillo

bioRxiv · Jul 27, 2024 · PreprintNeuroscience

TREM2-H157Y Increases Soluble TREM2 Production and Reduces Amyloid Pathology

Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden, Cristine M. Charlesworth, Yuka A. Martens, Chia‐Chen Liu, Joshua A. Knight, Tadafumi C. Ikezu, Aishe Kurti, Yiyang Zhu, Axel D. Meneses, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Lucy K. Vanmaele, , Guojun Bu

This study shows that the TREM2-H157Y mutation increases soluble TREM2 and reduces amyloid pathology in mice, suggesting a potential protective effect against Alzheimer's disease.

Molecular Neurodegeneration · Jan 31, 2023Peer-reviewedNeuroscience