Jun Zhong

This study shows that TBK1 and IKKε protect target cells from IFNγ-mediated T cell killing by suppressing inflammatory apoptosis and NFκB-driven inflammation.

This study shows that PP2A catalytic subunit alpha is essential for CD8+ T cell homeostasis and anti-bacterial responses, with Bcl2 rescue limited to spleen.

This study shows that the TREM2-H157Y mutation increases soluble TREM2 and reduces amyloid pathology in mice, suggesting a potential protective effect against Alzheimer's disease.

This study identifies a novel interaction between TREM2 and TDP-43, showing TREM2 mediates microglial neuroprotection against TDP-43-related neurodegeneration.