Author

Jia Jia Zhang

Massachusetts Institute of TechnologyORCID 0000-0002-3003-4485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alireza GhanbarpouriD· 1 shared Avena C. RossiD· 1 shared Barrett M. PowelliD· 1 shared Bertina TelusmaiD· 1 shared Bradley S. MooreiD· 1 shared Carolyn Vargas· 1 shared Isabella Bolstad· 1 shared Joseph H. DavisiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Alireza GhanbarpourORCID

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2 papers

Recent·Most cited

An asymmetric nautilus-like HflK/C assembly controls FtsH proteolysis of membrane proteins

Alireza Ghanbarpour, Bertina Telusma, Barrett M. Powell, Jia Jia Zhang, Isabella Bolstad, Carolyn Vargas, Sandro Keller, Tania A. Baker, Robert T. Sauer, Joseph H. Davis

The paper presents structures of native FtsH-HflK/C complexes in E. coli, revealing an asymmetric nautilus-like assembly that facilitates membrane protein degradation.

The EMBO Journal · Mar 13, 2025Peer-reviewedBiochemistry

Avant-garde assembly-line biosynthesis expands diversity of cyclic lipodepsipeptide products

Jia Jia Zhang, Xiaoyu Tang, Tao Huan, Avena C. Ross, Bradley S. Moore

The paper reports the heterologous reconstitution of hybrid NRPS-PKS assembly lines that generate a combinatorial library of cyclic lipodepsipeptide protease inhibitors through non-standard biosynthetic mechanisms.

bioRxiv · Feb 25, 2019 · PreprintMolecular Biology