Abubakarr A. Koroma

This study shows that co-delivering PD-L1 with an AAV-expressed HIV-1 bNAb reduces anti-drug antibodies and improves bNAb expression and protection against HIV in rhesus macaques.

This study shows that co-delivering PD-L1 with AAV-delivered bNAb 10-1074 reduces ADA responses and improves bNAb durability in rhesus macaques.

This study evaluates AAV transgene cassettes for expressing 10-1074 antibody in nonhuman primates and mice, showing promoter and WPRE effects on expression levels and immune responses.