Priya Dhole

This study shows that co-delivering PD-L1 with an AAV-expressed HIV-1 bNAb reduces anti-drug antibodies and improves bNAb expression and protection against HIV in rhesus macaques.

This study shows that co-delivering PD-L1 with AAV-delivered bNAb 10-1074 reduces ADA responses and improves bNAb durability in rhesus macaques.

This study evaluates AAV transgene cassettes for expressing 10-1074 antibody in nonhuman primates and mice, showing promoter and WPRE effects on expression levels and immune responses.

This study evaluates hPBAE nanoparticles for delivering diRNA antivirals to the lungs, showing efficient uptake, nuclease resistance, and safety in golden hamsters.