Author

Karina Rodrigues-dos-Santos

Indiana Biosciences Research InstituteORCID 0000-0002-3012-7171Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Gitanjali RoyiD· 2 shared Michael A. KalwatiD· 2 shared Travis S. JohnsoniD· 2 shared Alan AttieiD· 1 shared Amber L. MosleyiD· 1 shared Andrea D. OrdoneziD· 1 shared Andrew T. TempliniD· 1 shared Anna GeisingeriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Gitanjali RoyORCID

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2 papers

Recent·Most cited

Unique and conserved endoplasmic reticulum stress responses in neuroendocrine cells

Karina Rodrigues-dos-Santos, Gitanjali Roy, Anna Geisinger, Sahiti Somalraju, Travis S. Johnson, Michael A. Kalwat

The paper identifies unique and shared transcriptional responses to ER stress in various endocrine cell types using mRNA sequencing.

Cells · Sep 30, 2025Peer-reviewedCell Biology

Target deconvolution of an insulin hypersecretion-inducer acting through VDAC1 with a distinct transcriptomic signature in beta-cells

Gitanjali Roy, Andrea D. Ordonez, Derk D. Binns, Karina Rodrigues-dos-Santos, Michael B Kwakye, George C. King, R. Kuntz, Noyonika Mukherjee, Andrew T. Templin, Zhi‐Yong Tan, Timothy I. Richardson, Emma H. Doud, Amber L. Mosley, Kathryn L. Schueler, Christopher H. Emfinger, , Michael A. Kalwat

This paper identifies VDAC1 as the target of SW016789, a hypersecretion inducer, and shows it causes distinct transcriptomic changes in beta-cells compared to ER stress.

Cell Reports · Jun 1, 2025Peer-reviewedCell Biology