Kathryn L. Schueler

This paper identifies VDAC1 as the target of SW016789, a hypersecretion inducer, and shows it causes distinct transcriptomic changes in beta-cells compared to ER stress.

The paper identifies genetic drivers of plasma lipoproteins in mice and links them to human lipid traits using QTL analysis and GWAS integration.

The paper identifies Abhd2 as an enzyme involved in metabolizing phosphatidylcholine and cardiolipin using genetic and lipidomic data from Diversity Outbred mice.

The paper presents a MapCap sequencing workflow to locate and count transgenic sequences in mice, identifying insertion sites and characterizing genetic variations in a diabetes model.

INFIMA identifies effector genes of GWAS variants by integrating multi-omics data from mice and applying it to diabetes-associated variants.

This study identifies genetic loci associated with gut microbiota composition and bile acid profiles in mice using QTL analysis and validation experiments.

The paper identifies Slco1a6 as a gene affecting gene expression in mouse pancreatic islets through eQTL analysis and functional studies.