Author

Lena Engelhard

TU Dortmund University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Daniel SummereriD· 3 shared Marlon Steven Zambrano-MilaiD· 2 shared Sidney M. BeckeriD· 2 shared Simone Eppmann· 2 shared Zeyneb Vildan CakiliD· 2 shared Angela SimeoneiD· 1 shared Benjamin C. BuchmulleriD· 1 shared Christian J. SchröteriD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiochemistry

Daniel SummererORCID

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Author profile →

3 papers

Recent·Most cited

HM-DyadCap - Capture and Mapping of 5-Hydroxymethylcytosine/5-Methylcytosine CpG Dyads in Mammalian DNA

Lena Engelhard, Damian Schiller, Marlon Steven Zambrano-Mila, Kotryna Keliuotyte, Benjamin C. Buchmuller, Shashank Tiwari, Jochen Imig, Angela Simeone, Christian J. Schröter, Sidney M. Becker, Daniel Summerer

HM-DyadCap captures and maps hmC/mC CpG dyads in mammalian DNA, revealing their enrichment in gene bodies and depletion at transcription start sites.

Nucleic Acids Research · Apr 15, 2026Peer-reviewedGenomics

Proteomics-Based Discovery of Symmetry-Specific Readers and Antireaders of 5-Formylcytosine in Mammalian DNA

Zeyneb Vildan Cakil, Lena Engelhard, Nina Seidel, Simone Eppmann, Tanja Bange, Daniel Summerer

The paper identifies symmetry-specific readers and anti-readers of 5-formylcytosine (fC) in mammalian DNA using proteomics, revealing how proteins recognize fC-containing CpG dyads with distinct symmetry preferences.

bioRxiv · Apr 12, 2026 · PreprintBiochemistry

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand-Symmetric and -Asymmetric 5-Hydroxymethylcytosine-Modifications in DNA

Lena Engelhard, Zeyneb Vildan Cakil, Marlon Steven Zambrano-Mila, Simone Eppmann, Tye I. Gonzalez, Rasmus Linser, Petra Janning, Sidney M. Becker, Daniel Summerer

The paper identifies tissue-specific readers and antireaders of symmetric and asymmetric hmC modifications in DNA using proteomics and promoter probe assays in human and mouse cells.

Advanced Science · Jan 4, 2026Peer-reviewedBiochemistry