Author

Leigh A. Knodler

University of VermontORCID 0000-0002-3028-2198Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1

Frequent Co-Authors

Eddy Cruz· 2 shared Johanna R. ElfenbeiniD· 2 shared Trina L. WestermaniD· 2 shared Aaditi Lele· 1 shared Aimee R. Greissl· 1 shared Alan G. GoodmaniD· 1 shared Alexander V. PredeusiD· 1 shared Amanda L. HaeberleiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Eddy Cruz

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 12, 2025

SLC11A2 affects nutritional immunity in the gastrointestinal epithelium

Emilia S. Norberg, Trina L. Westerman, Eddy Cruz…·Leigh A. Knodler

This study shows that SLC11A2 in intestinal epithelial cells restricts iron and manganese to limit Salmonella replication, highlighting its role in nutritional immunity.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedJul 14, 2025

PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing

Michael Hweemoon Lee, Araceli Pérez-López, Leigh A. Knodler…·Manuela Raffatellu

This study shows that PgtE protease in virulent Salmonella Typhimurium helps evade complement-mediated killing by cleaving C3, enabling systemic spread.

4 citations

mouseproteomics

𝕏 PostBluesky

MicrobiologyInfection and ImmunityPeer-reviewedSep 10, 2024

Pathogenic diversification of the gut commensal Providencia alcalifaciens via acquisition of a second type III secretion system

Jessica A. Klein, Alexander V. Predeus, Aimee R. Greissl…·Leigh A. Knodler

This study investigates the role of two type III secretion systems in Providencia alcalifaciens, showing their differential contributions to host interactions and pathogenicity.

13 citations

humanDrosophila

𝕏 PostBluesky