Benjamin Grädel

Optogenetic SH3 nanoclustering of SRC and HCK uncovers the functional specificity of these redundant kinases in macrophages.

This study uses optogenetic tools to reveal distinct functional roles of SRC and HCK kinases in macrophages, despite their redundancy.

Interplay between Rac1/RhoA and actin waves in giant epithelial cells : experiment and theory

The paper studies acto-myosin dynamics and Rho GTPase interactions in epithelial cells using live microscopy and theory, revealing wave propagation and annihilation mechanisms.

Tracking Coordinated Cellular Dynamics in Time-Lapse Microscopy with ARCOS.px

ARCOS.px tracks spatial clusters in time-lapse microscopy to study dynamic cellular structures and their interactions.

Real-time feedback control microscopy for automation of optogenetic targeting

This paper introduces a real-time feedback system for optogenetic targeting, enabling automated and adaptive stimulation based on live cell behavior.

Teach your microscope how to print: Low-cost and rapid-iteration microfabrication for biology

This paper introduces a low-cost microfabrication method using 3D printing and repurposed microscopes for biological applications, achieving micrometer precision without clean room infrastructure.

Convpaint - Universal framework for interactive pixel classification using pretrained neural networks

Convpaint provides an interactive pixel classification framework using pretrained CNNs or ViTs, integrated into the napari ecosystem for versatile image processing.

Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly

This study shows ARHGEF17 regulates actomyosin network disassembly by localizing at the lamella back and promoting RhoA activity through feedback mechanisms.

Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging.

This paper introduces ADeS, a deep learning system for detecting apoptosis in live-cell imaging with high accuracy and robustness across diverse conditions.