Niclas G. Karlsson

Mapping galectin-3 ligands in tear fluid establishes spliceoform-dependent lacritin binding

This study identifies new Gal-3 ligands in tear fluid, showing that lacritin's glycoforms and spliceoforms specifically bind Gal-3, influencing its biological functions.

Sialoglycans Modulate Siglec-5 - TLR4 Interactions in Osteoarthritis

The paper investigates how sialoglycans modulate Siglec-5-TLR4 interactions in osteoarthritis, showing sialylation patterns influence inflammation and joint integrity.

In-depth analysis of the tear fluid glycoproteome reveals diverse lacritin glycosylation and spliceoforms

This study uses mass spectrometry to analyze tear fluid glycoproteins, revealing novel glycosylation patterns and spliceoforms of lacritin and other clinically relevant proteins.

Predicting glycan structure from tandem mass spectrometry via deep learning

The paper introduces CandyCrunch, a deep learning model that predicts glycan structures from tandem mass spectrometry data with high accuracy, enabling high-throughput glycomics.

e-workflow for recording of glycomic mass spectrometric data in compliance with reporting guidelines

The paper describes an e-infrastructure for recording glycomic mass spectrometric data in compliance with MIRAGE reporting guidelines, enabling standardized data submission to a public repository.