Rebecca Louise Miller

The paper shows that O-glycans in LRP1's ligand-binding domains differentially modulate uptake of tau and amyloid beta, but not RAP or ApoE.

This paper develops ToF-SIMS for in-situ GAG analysis, identifying discriminatory ions and demonstrating its application in human and diabetic mouse models.

The paper introduces a streamlined method for analyzing GAG disaccharides using HILIC-MS/MS, applicable to diverse biological samples.

This study identifies that Siglec-7 and -15 recognize repeated clustered sulfo-sialo O-glycan motifs on specific O-glycoproteins, enhancing selectivity through multivalent interactions.

This study identifies four heterodimeric complexes involved in human chondroitin sulfate chain polymerization and proposes a non-processive, disruptive mechanism based on structural and functional analyses.

This study identifies chondroitin sulfate as a potential therapeutic target for type 2 diabetes through genetic and preclinical evidence showing its effects on glycemic control and insulin action.

The paper shows leukocytes express heparan sulfate glycocalyx, which is shed during psoriasis-like inflammation, promoting leukocyte migration into skin.

The paper describes an e-infrastructure for recording glycomic mass spectrometric data in compliance with MIRAGE reporting guidelines, enabling standardized data submission to a public repository.