Author

María I. Lázaro‐Peña

Albert Einstein College of MedicineORCID 0000-0002-3061-8835Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Carlos A. Díaz-BalzaciD· 4 shared Andrew V. SamuelsoniD· 2 shared Hannes E. BülowiD· 2 shared Ritika DasiD· 2 shared Adam B. CornwelliD· 1 shared Juilee ThakariD· 1 shared Leo T. H. TangiD· 1 shared Maisha RahmaniD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersGenetics

Carlos A. Díaz-BalzacORCID

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4 papers

Recent·Most cited

GeneticseLifePeer-reviewedJun 20, 2023

Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and systemically regulates longevity from serotonergic and GABAergic neurons

María I. Lázaro‐Peña, Adam B. Cornwell, Carlos A. Díaz-Balzac…·Andrew V. Samuelson

This study identifies HPK-1 as a neuronal transcriptional regulator that maintains proteostasis and extends longevity in C. elegans by modulating serotonergic and GABAergic pathways.

11 citations

C. elegansDNA methylation

𝕏 PostBluesky

GeneticsbioRxivPreprintApr 2, 2022

Neuroendocrine control of the proteostatic network by HPK-1 delays aging

María I. Lázaro‐Peña, Carlos A. Díaz-Balzac, Ritika Das, Andrew V. Samuelson

This study identifies HPK-1 as a neuronal regulator of proteostasis that delays aging through distinct serotonergic and GABAergic pathways.

DOI 10.1101/2022.04.02.486836

C. elegansproteomics

𝕏 PostBluesky

Developmental BiologyeLifePeer-reviewedJan 29, 2019

TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization

Leo T. H. Tang, Carlos A. Díaz-Balzac, Maisha Rahman…·Hannes E. Bülow

This study shows TIAM-1/GEF shapes dendrites in C. elegans by regulating F-actin localization without requiring its GEF activity.

51 citations

C. elegansexperimental assay

𝕏 PostBluesky

NeuroscienceGeneticsPeer-reviewedMar 20, 2018

Heparan sulfate molecules mediate synapse formation and function of male mating neural circuits in C. elegans

María I. Lázaro‐Peña, Carlos A. Díaz-Balzac, Hannes E. Bülow, Scott W. Emmons

The paper shows heparan sulfate modifications are essential for synapse formation in C. elegans male mating circuits, with specific roles for 3-O sulfation and interactions between neurexin and neuroligin.

21 citations

C. elegansexperimental assay

𝕏 PostBluesky