Scott W. Emmons

Functions of C. elegans neurons from synaptic connectivity

The paper analyzes updated connectomes of C. elegans to identify modular structures and uncover new neuronal circuits and functions.

Prediction of Interactions between Cell Surface Proteins by Machine Learning

This paper develops a machine learning framework to predict interactions between cell surface proteins, achieving over 70% accuracy in human proteins and validating results against experimental data.

Function of cell adhesion molecules in differentiation of ray sensory neurons in C. elegans.

The paper investigates the role of cell adhesion molecules in the differentiation and connectivity of ray sensory neurons in C. elegans, finding limited effects on axon trajectory and synaptic component accumulation in CAM mutants.

The synaptic organization in the C. elegans neural network suggests significant local compartmentalized computations

The paper examines synaptic organization in C. elegans neurons and finds that synapses cluster along neurites, supporting local compartmentalized computations.

A direct glia-to-neuron natural transdifferentiation ensures nimble sensory-motor coordination of male mating behaviour

The paper identifies a novel mechanism of sexual dimorphism in the nervous system through direct glia-to-neuron transdifferentiation during sexual maturation in C. elegans.

Beyond the connectome: A map of a brain architecture derived from whole-brain volumetric reconstructions

The paper presents a complete structure-function model of the C. elegans nerve ring by integrating volumetric reconstructions with synaptic and gap junctional connectomes, revealing modular organization and a reference core circuit.

The connectome of the Caenorhabditis elegans pharynx

The paper re-evaluates the connectome of the C. elegans pharyngeal nervous system using serial EM reconstruction, revealing a more detailed structure and sensory-motor characteristics.

Expressional artifact caused by a co-injection marker rol-6 in C. elegans

The paper identifies that the rol-6 co-injection marker in C. elegans causes unintended GFP expression in male-specific neurons, highlighting its limitations for precise expression studies.

Volumetric reconstruction of main Caenorhabditis elegans neuropil at two different time points

The paper reconstructs the C. elegans nerve ring at two time points and identifies three levels of wiring specificity, suggesting non-spatial factors contribute to synaptic and subcellular specificity.

Heparan sulfate molecules mediate synapse formation and function of male mating neural circuits in C. elegans

The paper shows heparan sulfate modifications are essential for synapse formation in C. elegans male mating circuits, with specific roles for 3-O sulfation and interactions between neurexin and neuroligin.

Multiple conserved cell adhesion protein interactions mediate neural wiring of a sensory circuit in C. elegans