Author

Lars Emil Larsen

Ghent UniversityORCID 0000-0002-3067-8459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:electronic health records· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:rat· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Robrecht RaedtiD· 4 shared Evelien CarretteiD· 3 shared Kristl E.J. VonckiD· 3 shared Paul BooniD· 3 shared Erine CraeyiD· 2 shared Jeroen SpanogheiD· 2 shared Marijke VergaeleniD· 2 shared Serge Van CalenberghiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Robrecht RaedtORCID

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4 papers

Recent·Most cited

tDCS Cranial Nerve Co-Stimulation: Unveiling Brainstem Pathways Involved in Trigeminal Nerve Direct Current Stimulation in Rats

Alireza Majdi, Liyi Chen, Lars Emil Larsen, Robrecht Raedt, Myles Mc Laughlin

This study investigates how trigeminal nerve direct current stimulation (TN-DCS) affects brainstem neuronal activity in rats, finding significant modulation in locus coeruleus and dorsal raphe nucleus but not median raphe nucleus.

Brain stimulation · Feb 5, 2025Peer-reviewedNeuroscience

Photopharmacological activation of adenosine A1receptor signaling suppresses seizures in a mousemodel for temporal lobe epilepsy

Jeroen Spanoghe, Paul Boon, Marijke Vergaelen, Maren De Colvenaer, Tina Mariman, Kristl E.J. Vonck, Evelien Carrette, Wytse Jan Wadman, Erine Craey, Lars Emil Larsen, Mathieu Sprengers, Jeroen Missinne, Serge Van Calenbergh, Dimitri De Bundel, Ilse Julia Smolders, Robrecht Raedt

This study demonstrates that photopharmacological activation of A1R reduces seizures in a mouse model of temporal lobe epilepsy with fewer side effects than systemic administration.

bioRxiv · Jul 4, 2024 · PreprintNeuroscience

Feedback Control of Neuronal Excitability and Epileptiform Bursting using a Photocaged Adenosine A1 Agonist

Erine Craey, Serge Van Calenbergh, Jeroen Spanoghe, Marijke Vergaelen, Lars Emil Larsen, Evelien Carrette, Jean Delbeke, Kristl E.J. Vonck, Paul Boon, Wytse Jan Wadman, Robrecht Raedt

This study uses a photocaged adenosine A1 agonist in a closed-loop system to control neuronal excitability and suppress epileptiform bursting in hippocampal slices.

bioRxiv · Jun 17, 2024 · PreprintNeuroscience

Modulation of locus coeruleus neurons and strong release of noradrenaline during acute hippocampal seizures in rats

Lars Emil Larsen, Sielke Caestecker, Latoya Stevens, Pieter van Mierlo, Evelien Carrette, Paul Boon, Kristl E.J. Vonck, Robrecht Raedt

bioRxiv · Mar 6, 2023 · PreprintNeuroscience